Oroboros Instruments

Oroboros Instruments Oroboros Instruments distributes the gold standard for O2k-technology High-Resolution Respirometry. We are a scientifically oriented organization.

On World Brain Tumor Day, we emphasize the growing importance of metabolism and mitochondrial research in advancing our ...
08/06/2026

On World Brain Tumor Day, we emphasize the growing importance of metabolism and mitochondrial research in advancing our understanding and treatment of brain tumors.
Martell et al. used high-resolution respirometry to characterize glioblastoma cells with a mitochondrial metabolic phenotype. Patient samples following temozolomide and radiation therapy showed increased respiratory activity, revealing a potential metabolic vulnerability that could be therapeutically targeted.
Studies like this deepen our understanding of how metabolic rewiring and mitochondrial function shape brain tumor progression and open new avenues for targeted therapies.
Read 📖: https://buff.ly/9Ovnovr

Author affiliations:
Rady Faculty of Health Sciences, University of Manitoba
University of Manitoba: Faculty of Science
CancerCare Manitoba Research
McMaster University
Texas Children's
Baylor College of Medicine

Funding:
Canadian Institutes of Health Research
Canadian Cancer Society
Société de recherche sur le cancer / Cancer Research Society
Health Sciences Centre Foundation

It has been a busy week for our team across , , and -E.Great to see colleagues sharing their work, discussing new ide...
05/06/2026

It has been a busy week for our team across , , and -E.

Great to see colleagues sharing their work, discussing new ideas, and connecting with the wider research community.

Catch Erich Gnaiger and Elettra Leo next week at
https://buff.ly/Jnub3tI

Residual oxygen consumption 𝘳𝘰𝘹 is due to oxidative side reactions remaining after inhibition of the electron transfer p...
03/06/2026

Residual oxygen consumption 𝘳𝘰𝘹 is due to oxidative side reactions remaining after inhibition of the electron transfer pathway. Mitochondrial respiration is frequently corrected for 𝘳𝘰𝘹 as the baseline state and this correction can be performed directly in DatLab to display the normalized plot.
Learn more:
👉https://buff.ly/eI6QbF6
👉https://buff.ly/CfD8hRo

Our team will also be attending -E next week!Sabine Schmitt will present:“Oxygen dependence of hydrogen peroxide produc...
29/05/2026

Our team will also be attending -E next week!

Sabine Schmitt will present:
“Oxygen dependence of hydrogen peroxide production in isolated mitochondria and permeabilized cells”
https://buff.ly/8hYLmtU

If you’re attending the meeting, come by the poster and say hello — we’d be delighted to connect and discuss the research.

We’re excited to be presenting at next week!Our team will share two poster presentations:🗓 Tuesday, June 2 | 13:25–15:...
29/05/2026

We’re excited to be presenting at next week!

Our team will share two poster presentations:

🗓 Tuesday, June 2 | 13:25–15:25
“Diagnostic OXPHOS Precision Analysis with Cryopreserved PBMCs”
Poster presentation by Alejandra Romero Martinez
https://buff.ly/ortEw8j

🗓 Wednesday, June 3 | 13:25–15:25
“Optimization of Human PBMC Isolation to Preserve Viability and Mitochondrial Function for Diagnostic Applications”
Poster presentation by Jaime Willis
https://buff.ly/L97on5l

We look forward to connecting with fellow researchers and discussing our latest work.

We’re looking forward to attending next week!Elettra Leo will present:“Mitochondrial Ca2+ uptake is constrained in an ...
29/05/2026

We’re looking forward to attending next week!

Elettra Leo will present:
“Mitochondrial Ca2+ uptake is constrained in an exercise-mimicking model of functional hypoxia” https://buff.ly/OuNt25z

🗓 Monday, June 1
⏰ 01:15–02:30 pm
📍 Session 6: Hot Topic: GLP1 agonists, Skeletal Muscle and Exercise
🪧 Poster #5024

If you’re attending, stop by the poster and say hello — we’d love to chat about the work.

Select the sample addition method based on your sample type: full or partial volume replacement, or direct titration int...
28/05/2026

Select the sample addition method based on your sample type: full or partial volume replacement, or direct titration into the Oroboros chamber using a Hamilton syringe for precise control. For non-pipettable samples (e.g., muscle fibers), place them directly into the chamber. Using the Sample Holder c𝘝 helps protect delicate material from damage caused by stirring.
Learn more 👉https://buff.ly/olJtzns , https://buff.ly/S3dTAnj

The oxygen solubility factor of the respiratory medium 𝘍M depends on temperature and medium composition. In MiR05 and Mi...
21/05/2026

The oxygen solubility factor of the respiratory medium 𝘍M depends on temperature and medium composition. In MiR05 and MiR06, 𝘍M is 0.92 (determined at 30 °C and 37 °C; assumed identical at 25 °C), while in culture media it is 0.89 (at 37 °C). For other media, 𝘍M can be estimated by treating KCl-based media as “seawater” of varying salinity.
Learn more: https://buff.ly/NT1im3x

The POS service manual describes how to perform cathode and anode cleaning, cleaning of electrical connections, and memb...
19/05/2026

The POS service manual describes how to perform cathode and anode cleaning, cleaning of electrical connections, and membrane mounting. These steps are essential to ensure signal stability, low noise, and high time-resolution.
https://buff.ly/0wo3DaZ

Last week, three of our team members took part in the Innsbruck Alpine Trailrun Festival and achieved 3ʳᵈ place in the ...
06/05/2026

Last week, three of our team members took part in the Innsbruck Alpine Trailrun Festival and achieved 3ʳᵈ place in the Women’s Business Trail!🥉
A great example of mitochondria in action — in research and on the trail.

Congratulations to Team Oroboros LAB - Lisa, Ana and Bente! 🎉

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Schoepfstrasse 18
Innsbruck
6020

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Dienstag 09:00 - 12:00
13:00 - 16:00
Mittwoch 09:00 - 12:00
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Freitag 09:00 - 17:00

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