12/02/2013
. Definitions of Selected Hematologic Changes :
Anemia
Decreased red blood cell (RBC) mass, clinically noted by decreased packed cell volume (PCV) .....................................................
Polycythemia
Increased RBC mass in body (increased PCV).......................................
Polychromasia
Increased number of polychromatophils
Poikilocytosis
Increased variation in RBC shapes
Microcytosis
Increased number of small RBCs
Macrocytosis
Increased number of large RBCs
Normocytic
RBCs are of normal size
Hypochromic
RBCs have lower hemoglobin (Hgb) concentration (lower mean
corpuscular Hgb concentration [MCHC])
Normochromic
RBCs have normal MCHC
Spherocytosis
Increased number of spheric RBCs
Echinocytosis
Increased number of RBCs with many spiny projections
Acanthocytosis
Increased number of RBCs with a few elongated, rounded projections
RBC
fragmentation Increased number of small RBC fragments, RBCs with extensions ready to break off, or both
Rouleaux
Formation of RBCs into linear formations resembling stacks of coins
Autoagglutination
Immune aggregation of RBCs into grapelike clusters
Heinz bodies
Precipitated Hgb resulting from oxidation
Thrombocytopenia
Decreased number of platelets
Thrombocytosis
Increased number of platelets
Leukocytosis
Increased number of white blood cells (WBCs)
Leukopenia
Decreased number of WBCs
Neutrophilia
Increased number of neutrophils
Neutropenia
Decreased number of neutrophils
Left shift
Increased number of immature neutrophils (nonsegs)
Right shift
Increased number of hypermature neutrophils (hypersegmentation)
Toxic neutrophils
Neutrophils with certain morphologic changes
Reactive lymphs
Lymphocytes with certain morphologic changes
Monocytosis
Increased number of monocytes
Monocytopenia
Decreased number of monocytes
Lymphocytosis
Increased number of lymphocytes
Lymphopenia
Decreased number of lymphocytes
Eosinophilia
Increased number of eosinophils
Eosinopenia
Decreased number of eosinophils
Basophilia
Increased number of basophils
Basopenia
Decreased number of basophils
Bicytopenia
Decrease in two cell lines (RBCs, WBCs, or platelets)
Pancytopenia
Decrease in three cell lines (RBCs, WBCs, and platelets)