HKU School of Biomedical Sciences

HKU School of Biomedical Sciences School of Biomedical Sciences
Li Ka Shing Faculty of Medicine
The University of Hong Kong https://linktr.ee/hkusbms

🌟 Congratulations to Prof. Tiago Rito on being named an IBRO Rising Star Awardee! 🧠✨Presented by the International Brain...
22/06/2026

🌟 Congratulations to Prof. Tiago Rito on being named an IBRO Rising Star Awardee! 🧠✨

Presented by the International Brain Research Organization (IBRO), the Rising Stars Awards recognise outstanding early-career neuroscientists and support their transition to independent research careers. The award provides essential funding to help recipients establish and advance their own laboratories, empowering the next generation of leaders in neuroscience.

Prof. Rito was selected through a highly competitive process, reflecting the significance and promise of his research contributions. This international recognition highlights his commitment to advancing brain science and fostering innovation in the field.

We are proud to celebrate this remarkable achievement and look forward to the exciting discoveries and impact that lie ahead.

Congratulations once again, Prof. Rito! 👏

  has signed a Memorandum of Understanding with   AI to bridge biomedical education with frontier artificial intelligenc...
09/06/2026

has signed a Memorandum of Understanding with AI to bridge biomedical education with frontier artificial intelligence. 🤝

VoteeAI built the world's first open-source Cantonese large language model 🗣️, currently deployed on-premise across banking, government, FMCG and telecommunications customers.

This strategic partnership accelerates the translation of biomedical discoveries into digital health products, reinforcing Hong Kong's position as an international health and medical innovation hub by establishing a structured pipeline for:

💡 𝗔𝗽𝗽𝗹𝗶𝗲𝗱 𝗔𝗜 𝘁𝗿𝗮𝗶𝗻𝗶𝗻𝗴 and joint research and development.
💼 𝗦𝘁𝗿𝘂𝗰𝘁𝘂𝗿𝗲𝗱 𝗶𝗻𝘁𝗲𝗿𝗻𝘀𝗵𝗶𝗽 𝗼𝗽𝗽𝗼𝗿𝘁𝘂𝗻𝗶𝘁𝗶𝗲𝘀 for undergraduate and postgraduate students, where interns engage not only with Votee AI but also with the broader ecosystem of its strategic partners.

Looking forward to a successful collaboration that will drive impactful healthcare solutions and cultivate top-tier technological talent! 🚀

🔗 Check out the full press release: https://www.sbms.hku.hk/press/hkumed-school-biomedical-sciences-and-votee-ai-sign-mou-launch-student-internships-and-joint

05/06/2026

🎉 Cell Scientist to Watch: Prof. Mu He 🔬

Huge congratulations to Prof. Mu He on being featured by the Journal of Cell Science, where she shares her inspiring journey—from discovering microscopic patterns with her childhood microscope to the realities of launching a lab during a pandemic. We are incredibly proud to have such a trailblazing young faculty member leading the way and mentoring the next generation of biomedical scientists at HKU! 🚀🎓

🔗 Link for the full interview: https://journals.biologists.com/jcs/article/139/11/jcs265008/371876/Cell-scientist-to-watch-Mu-He
👉 Discover the He Lab: https://www.muhelab.com/

That’s a wrap on our annual RPG Symposium! 🎓✨It was fantastic to see members from across the entire school come together...
29/05/2026

That’s a wrap on our annual RPG Symposium! 🎓✨

It was fantastic to see members from across the entire school come together for an incredible day of scientific exchange. Mirroring the success of last year's event, this year's programme featured an inspiring keynote lecture from Prof. Tiannan Guo, Westlake University, alongside vibrant oral presentation panels and dynamic poster sessions.

A special shoutout to our full-time MPhil and PhD students who stepped up to the podium for their oral presentations, as well as our 2nd-year PhD students who showcased their research during the poster sessions. Thank you for bringing such high-calibre insights to the floor and continuing to elevate our research community!

Thank you to everyone who attended, presented, and contributed to making this year's symposium a resounding success.

28/05/2026
26/05/2026

SBMS Emeritus Professor, Prof Danny Chan, and his team sat down with the Croucher Foundation for an exclusive Q&A to break down their game-changing stem cell research.

Instead of just looking at the data, the feature tackles the real questions: How do you stop the body from rejecting transplanted cells? How do you keep it safe for patients? And what does this actually mean for the future of medicine?

🔗 Read the full story: https://croucher.org.hk/en/news/stem-cells-designed-to-evade-immune-rejection

Check out HKUMed's full interview with Professor YS Chan at https://medium.com/hkumed/%E6%95%99%E5%AD%B8%E7%9B%B8%E9%95%...
18/05/2026

Check out HKUMed's full interview with Professor YS Chan at https://medium.com/hkumed/%E6%95%99%E5%AD%B8%E7%9B%B8%E9%95%B7-%E7%95%B6%E7%A5%9E%E7%B6%93%E7%A7%91%E5%AD%B8%E5%AE%B6%E9%81%87%E4%B8%8A%E5%AF%82%E9%9D%9C%E7%9A%84%E6%9C%8B%E5%8F%8B-551b1656f5ec

【教學相長】當神經科學家遇上寂靜的朋友

電影《寂靜的朋友》近日在香港公映,主角之一是由梁朝偉飾演的「神經科學家」。作為研究人體內最神秘、最複雜的大腦的人,到底一位神經科學家的日常是怎樣呢?又是否如電影名稱般是位性格寂靜、終日沉醉於研究的朋友?今天,小編找了從事超過30年神經科學研究的港大醫學院生物醫學學院陳應城教授為大家解構「神經科學家」這個特別職業。

回憶起當初為什麼會對神經科學感興趣時,陳教授分享:「我大學本科時在香港大學就讀了一個關於人體神經科學的課程。當時認識到神經科學其實影響著每個人的思想、感情、行為,但仍是一個有許多未解之謎的領域。因而激發起我的求知欲,很想透過神經科學的研究來找出大腦的秘密。」

破解腦內的「導航」機制

其中一個吸引陳教授全情投入尋索的是腦內的導航系統。每天如何從公司回到熟悉的家中,甚至出國旅行時在異鄉街頭找出回酒店的路,都先得找出自己的定位,按著指示一步一步前往目的地。要成就這件事,全賴每個人腦中天生已有的一套「導航系統」。這套系統讓每個人知道自己身處的位置和空間,繼而接受周遭環境傳遞出的信息、經驗儲存起來,從而推斷得到如何從一個地方前往另一個地方,好讓每個人不會錯走「冤枉路」。

2014年,三位科學家因為發現決定大腦定位系統的細胞,而共同獲頒諾貝爾生理學或醫學獎。他們發現每個人的導航系統,是由於腦中樞內不同組別的「導航神經細胞」一同協作。該系統讓人知道自己身處甚麼位置,如何前往目的地。這些發現啓發了陳教授其中一個研究範疇。

辨別方向與導航能力,是人類與動物賴以生存的重要認知功能。與記憶或注意力等其他認知功能相比,導航能力常在老年階段較早出現顯著的衰退,導致方向感下降、獨立生活能力減弱,甚至增加癡呆風險。然而,衰老過程中導致導航認知下降的具體神經通路及其細胞機制尚未有定論。

去年,陳教授與研究團隊在頂尖國際期刊《Nature Aging》中發表了研究論文,指出「導航系統」與特定的神經連結有密切關係。陳教授解釋:「我們在成年小鼠發現一條先前未被發現的神經通路,確保前庭資訊快速而靈活地傳遞至大腦高級中樞。當這通路被抑制時,小鼠的導航表現顯著下降。而在老年小鼠,該通路的連接數量明顯減弱,表明其與衰老相關的導航功能退化密切相關。令人振奮的是,選擇性地激活剩餘的神經通路,能有效恢復老年小鼠的導航能力。」這也意味著,利用新興的精準基因遞送,有望增強該通路內的細胞功能,透過多期臨床試驗,應可幫助長者或癡呆患者改善導航功能及認知障礙。

充滿科幻感的未來醫學

陳教授坦言人腦依然有很多可待開發的地方,因此未來的醫學發展,仍有無盡的可能。我們不時在媒體上聽到運動員因脊椎損傷,而導致四肢癱瘓,失去控制身體及肢體的活動能力。陳教授指:「脊椎受傷會引致脊髓內出血和產生疤痕,阻斷神經訊息傳遞。」而陳教授和研究團隊透過老鼠模型,成功將人體骨髓內的前驅細胞在數天內快速轉化為神經膠質細胞,並將這些細胞移植到受傷老鼠的脊髓損傷處,發現藉著「神經可塑性」(Neuroplasticity)這個機制,能使受傷老鼠們顯著改善行走和爬梯子的能力。他補充,這類細胞療法其實在科學界已經開展了不少臨床研究。

因此,如果日後我們在健康狀態下到醫院抽取組織,再置存於生物樣本庫(Biobank),在有需要時再快速培育出特定的目標細胞,幫助受損的神經系統重新連接,從而提升康復速度。陳教授笑說,在人工智能的推動下,這個看似遙不可及的想像,可能在十多年後便可面世,惠及人羣。

當神經科學家遇上一位寂靜的朋友

在電影《寂靜的朋友》中,梁朝偉飾演神經科學家Tony Wong博士 。梁朝偉接受媒體訪問時指為了演繹好神經科學家這角色,花了相當長時間去準備,更到訪不同大學跟神經科學家「取經」,而陳應城教授也是他的「研究」對象之一。

陳應城教授分享:「我與梁朝偉有數次見面,他希望瞭解一個神經科學家的日常生活和工作模式,因此我向他分享自己的教學及研究工作。」被問及會否跟映畫中人一樣,跟植物交流,陳教授笑言面對龐大工作量時,自己也會透過散步和遠足解壓:「在大自然中漫步有助我清空思緒,有時甚至能為我帶來新的研究靈感。」

在電影中,梁朝偉專注於研究嬰兒的早期發育認知,因此向陳教授表示他很希望能夠身歷其境。陳教授帶他前往觀察神經科學的實驗是如何進行,亦參觀兒童腦神經科的臨床研究。相處時間不長,但陳教授形容梁朝偉温文爾雅、平易近人,亦是一位非常專注及專業的演員。「他甚至試圖研究及觀察我們在做雷射螢光顯微鏡的成像實驗時,手部動作應該如何呈現。」由於電影導演介紹了梁朝偉看了幾本關於神經科學的書,所以他也向陳教授請教了一些神經科學的概念,例如陳教授的研究中有應用到的「神經可塑性」。「當時我向他解釋,每當學習新知識或技術時,腦內的神經網絡也會建立新的連接,大腦透過『神經可塑性』其實是不斷在重塑。這個核心機制亦對腦部創傷與中風後的康復起關鍵作用。」

實驗室以外的神經科學家

除了是一位神經科學家,陳應城教授亦有「多重身份」。他是港大醫學院校園發展及基建總監,當中沙宣道6號臨床培訓設施中心便是其中一個核心發展項目,以提供足夠的教學空間及設施,支援持續增長的醫學生數目,配合醫學院長遠發展的需求。

在今年11月,U21健康科學組織 (U21 Health Sciences Group)的年度會議將於港大醫學院舉行,陳教授正正是這跨國組織的副理事長及秘書處總監,需經常與世界各地的醫學院進行交流、舉辦各項學術活動。他分享,今年的主題是關於人工智能如何在多元文化世界融入醫學教育及實踐。

陳教授也笑說外間有時候會對神經科學家有一些刻板印象:「我們並不是每天都待在實驗室內,24小時拿著試管、手術刀或看著顯微鏡,拒絕社交。事實上,我們也參與大學的行政工作,專業協會的研習探討及國際學術學會的跨領域交流,亦經常參與不同範疇的社區活動, 藉以促進知識交流和人才培育,所以並不是大家想像中的『科學怪人』。」

完整文章:https://medium.com//教學相長-當神經科學家遇上寂靜的朋友-551b1656f5ec

有關在頂尖國際期刊《Nature Aging》論文連結:https://www.nature.com/articles/s43587-025-00884-4

#港大醫學院

Congratulations to   Professor Kathryn Cheah for being selected as a foreign member of Academia Europea in the Cell and ...
12/05/2026

Congratulations to Professor Kathryn Cheah for being selected as a foreign member of Academia Europea in the Cell and Developmental Biology section! 💐

【最新消息】港大醫學院生物醫學學院謝賞恩教授獲選歐洲科學院外籍院士

歐洲科學院(Academia Europaea)公佈2026年院士名單,港大醫學院生物醫學學院榮休講座教授謝賞恩教授獲選為歐洲科學院外籍院士,以表彰謝教授於生物醫學領域的貢獻及卓越成就。

謝賞恩教授是一位國際知名發育遺傳學家,致力於研究遺傳性和退化性骨骼疾病的遺傳與分子機制。她透過人類和小鼠胚胎幹細胞以及基因改造的小鼠模型來進行研究,並開發治療軟骨疾病(如骨關節炎)、骨質疏鬆症和椎間盤退化等疾病的方法。在2021年,謝教授當選為香港科學院院士;2022年,她獲頒英國基質生物學會獎章 (BSMB Medal Award) ;2023年,她被選為歐洲分子生物學組織(EMBO)外籍會士。EMBO是由超過2000位來自歐洲及全球的頂尖生命科學家組成,當中91位是諾貝爾獎得主,謝教授是首位獲得此殊榮的香港人。

在此,港大醫學院祝賀謝賞恩教授榮獲殊榮!

#港大醫學院

"𝗪𝗶𝘁𝗻𝗲𝘀𝘀𝗶𝗻𝗴 𝗿𝗲𝘀𝗲𝗮𝗿𝗰𝗵 𝗴𝗿𝗼𝘄 𝗳𝗿𝗼𝗺 𝗰𝗼𝗻𝗰𝗲𝗽𝘁 𝘁𝗼 𝗰𝗹𝗶𝗻𝗶𝗰𝗮𝗹 𝗿𝗲𝗮𝗹𝗶𝘁𝘆..."Recently, we had the chance to sit down with our PhD alumn...
11/05/2026

"𝗪𝗶𝘁𝗻𝗲𝘀𝘀𝗶𝗻𝗴 𝗿𝗲𝘀𝗲𝗮𝗿𝗰𝗵 𝗴𝗿𝗼𝘄 𝗳𝗿𝗼𝗺 𝗰𝗼𝗻𝗰𝗲𝗽𝘁 𝘁𝗼 𝗰𝗹𝗶𝗻𝗶𝗰𝗮𝗹 𝗿𝗲𝗮𝗹𝗶𝘁𝘆..."
Recently, we had the chance to sit down with our PhD alumnus ('23), Dr He Yi, to catch up on his incredible journey since graduation.

Co-founding Nordia Biotech alongside Professor Zhou Zhongjun, He Yi’s work is on stem cell-derived islet organoids for diabetes treatment.

Reflecting on four years of "hard work, trial and error," He Yi shared how meaningful it has been to see his PhD research finally "take off" and move toward clinical testing (pre-IND). For him, it’s about more than just data—it’s about the potential to transform lives through biotechnology.

𝗔𝗿𝗲 𝘆𝗼𝘂 𝘀𝘁𝗶𝗹𝗹 𝗱𝗲𝗰𝗶𝗱𝗶𝗻𝗴 𝘆𝗼𝘂𝗿 𝗻𝗲𝘅𝘁 𝗺𝗼𝘃𝗲 𝗶𝗻 𝘁𝗵𝗲 𝘄𝗼𝗿𝗹𝗱 𝗼𝗳 𝗕𝗶𝗼𝗺𝗲𝗱?
If you’re inspired by stories of innovation and want to explore new career frontiers in digital health or molecular biotechnology, join us this Friday for our online webinar.

💡 Online Information Session: Master of Biomedical Innovation
📅 15/5 (Friday) 20:00 - 21:00 HKT
👉 Register and start your own journey at https://hku.au1.qualtrics.com/jfe/form/SV_bxXvmj1yDfjyQnQ

🔬What happens when curiosity meets clarity?Through every lens, a different frontier emerges. From decoding the human bra...
08/05/2026

🔬What happens when curiosity meets clarity?

Through every lens, a different frontier emerges. From decoding the human brain to engineering life at the molecular level, our research doesn’t just observe—it advances.

At the School of Biomedical Sciences, our researchers work across disciplines, scales, and technologies—united by one purpose: pushing biomedical sciences further, with rigour and impact, where fundamental research can become future solutions.

Five research areas. One shared focus on discovery. Celebrating our 10th anniversary with a new website look—and an ongoing commitment to scientific excellence. Look closer into the insights and meet the minds behind them👉https://www.sbms.hku.hk/

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