National Institute of Molecular Biology and Biotechnology UP Diliman

01/09/2026

📑NIMBB FEATURED PUBLICATION 👏👏👏

Article:
Phosphoproteomic Profiling of Early-Stage Non-Small Cell Lung Cancer Provides Preliminary Evidence of Phosphorylation-Regulated Rho GTPase Signaling Driving Cytoskeletal Remodeling, Angiogenesis, and Cell Cycle Progression

Authors:
Baby Rorielyn T. Dimayacyac-Esleta, Lara Beatrice L. Suñga, Lorenzo M. Zarate, Ferdinand D. Mira, Ben Joshua O. Porras, Dave Laurence A. Juntilla, Venus B. Pondevida, Eloise I. Prieto

DOI: https://doi.org/10.1021/acs.jproteome.6c00453

28/08/2026

Itinuturing na non-model species ang mga alimango (mud crabs). Nangangahulugan itong limitado lamang ang mga genomic resource na magagamit ng mga siyentipiko para pag-aralan ang mga ito kumpara sa mga organismong masusing napag-aralan na. Upang suriin ang mga gill at hepatopancreas ng mga alimango—isang organ na sangkot sa pagtunaw ng pagkain at pag-iimbak ng sustansya—gumamit ng high-throughput sequencing si Gardel Xyza Silvederio mula sa National Institute of Molecular Biology and Biotechnology UP Diliman at UP Marine Science Institute ng University of the Philippines–Diliman College of Science, kasama sina Dr. Ma. Anita Bautista ng NIMBB, at Angela Camille Aguila-Toral at Dr. Rachel June Ravago-Gotanco ng MSI.

Kayang iproseso ng bioinformatics pipeline na ito ang napakaraming impormasyong henetiko nang sabay-sabay. Dahil dito, natutukoy at napag-aaralan ng mga siyentipiko ang mga gene ng alimango nang hindi na umaasa sa isang kumpletong reference genome. Gumamit sila ng limang magkakaibang assembly tool upang pagsamahin ang impormasyong henetiko: Trinity, SOAPdenovo-Trans, IDBA-Trans, rnaSPAdes, at EvidentialGene. Sa mga ito, ang Trinity ang nagpakita ng pinakamahusay na resulta para sa datos ng parehong gill at hepatopancreas. Natuklasan din nila na ang paggamit ng iba't ibang metric ay nakatutulong sa pagtatasa ng kalidad ng transcriptome. Ang mga nabuong transcriptome ay makatutulong sa mga siyentipiko para sa mga darating pang pananaliksik sa genomics at gene expression analysis sa mga alimango. Nagbibigay din ang pag-aaral na ito ng isang maaasahang pamamaraan para sa pag-aaral ng mga gene ng iba pang non-model species.

Ang pag-aaral na ito ay pinondohan ng Department of Science and Technology–Philippine Council for Agriculture, Aquatic, and Natural Resources Research and Development (DOST PCAARRD).

Link sa pag-aaral: https://philjournalsci.dost.gov.ph/evaluation-of-de-novo-assembled-transcriptomes-from-a-non-model-organism-scylla-serrata/

Ang Science Flash ng College of Science ay ginawa para ibahagi, sa mas simple at mabilis na paraan, ang mga bagong pag-aaral ng ating mga siyentipiko. Kung may gustong panayam o may tanong para sa media, mag-email lang sa media(at)science.upd.edu.ph.

Isninalin ni: Mary Ann Corrales

28/08/2026

Three days left before the signups for the UPD-NIMBB Training Program closes 🧬

Worried about costs? Lunch and snacks will be covered for all participants. Furthermore, we are pleased to announce that free accommodations will be provided to participants from Regions I, II, IV-B, V, and those from Visayas and Mindanao.

Interested participants may register through the online form accessible via the following link:
https://forms.gle/UHpJLFCrmhLvUYZP9

For further inquiries, email Dr. Ma. Anita M. Bautista at [email protected]

24/08/2026

24/08/2026

Ready to ?

The UP Diliman - National Institute of Molecular Biology and Biotechnology (UPD-NIMBB) will conduct a series of hands-on training sessions in basic molecular biology techniques from December 11 - 12, 2026.

The training session will be catered towards public high school STEM teachers with little to no experience in standard molecular biology laboratory techniques.

The 2-day training series will cover Bacterial DNA Extraction, Polymerase Chain Reaction, Nucleic Acid Quantification, and Basic Bioinformatics.

Interested participants may register through the online form accessible via the following link:
https://forms.gle/UHpJLFCrmhLvUYZP9

Please do note that filling out the form does NOT automatically guarantee a slot in the training. Potential participants will be screened and notified of their acceptance via email. The deadline for filling up this form is on August 31, 2026 at 5:00 PM.

For further inquiries, email Dr. Ma. Anita M. Bautista at [email protected]

24/08/2026

The UP Diliman College of Science proudly congratulates our Dean, Dr. Cynthia P. Saloma, for being selected as one of the recipients of the 2026 Iloilo City Mayor's Citation.

The Mayor's Citation is the highest recognition awarded by the Iloilo City Government to Ilonggos who have exemplified excellence in their respective fields and dedicated service towards the progress of Iloilo City and its people. This year's recipients will be recognized during the Mayor's Dinner on August 25, 2026.

17/08/2026

In accordance with Memorandum Circular No. 128, issued by the Office of the President and posted on the Presidential Communications Office page, the UP Diliman (UPD) Office of the Chancellor announced that UPD will observe alternative arrangements for classes and work (except for essential offices) tomorrow, 18 August 2026.

Stay safe.

17/08/2026

🚨 ATTENTION: STRANDED UPD STUDENTS

Due to heavy rains and flooding across the campus, the lobbies and common areas of all UPD Residence Halls are open as temporary emergency shelters for stranded students.

📌 Guidelines for Entry:
• Please present your UP ID upon entry.
• Coordinate directly with the resident dorm personnel on duty.

Stay safe, dry, and take care, Iskolars! 🌧️☔

17/08/2026

The UP Diliman Office of the Chancellor issued a memorandum on the extension of the deadline of payment for the first semester of Academic Year 2026–2027.

The memorandum can also be accessed at https://upd.edu.ph/memorandum-no-eclv-26-032-extension-of-deadline-of-payment-for-the-first-semester-ay-2026-2027/.

17/08/2026

In accordance with Memorandum Circular No. 127 issued by the Office of the President and posted on the Presidential Communications Office’s page, the UP Diliman (UPD) Office of the Chancellor announced that work at UPD (except for essential services) will observe alternative arrangements for classes and work today, 17 August 2026, starting 12 p.m.