ATDD_Research Group

10/02/2023

Recently, Jacinta Pinho and Manuela Gaspar, from , with the collaboration of researchers from iMed.ULisboa, IST, Universities of Coimbra and Utrecht have published in Biomedicine & Pharmacotherapy Journal a pre-clinical study of liposomes containing a new dual acting hybrid molecule against melanoma (https://doi.org/10.1016/j.biopha.2022.114021).

Furthermore, these results were featured, this week, on ASPIC, the Portuguese Association for Cancer Research (https://www.aspic.pt/en/noticias/preclinical-validation-new-hybrid-molecule-loaded-liposomes-melanoma-management #.Y-aZZnbP3Ms).
The relevance of the developed work comprises the in vitro and in vivo validation of a newly synthesized hybrid molecule. Particularly, after incorporation in liposomes this nanoformulation exhibited higher antitumor effect towards subcutaneous and metastatic melanoma, compared to approved drugs, dacarbazine and temozolomide, devoid of toxic side effects.

Congratulations to all the authors that took part in this work of extreme importance!

16/12/2022

The group is once again to be congratulated for a new achievement: two of our group members are among the World’s Top 2% Scientists 2022, a list from Elsevier data base reporting the most cited researchers worldwide. Congratulations to our group leader Professor António Almeida, and member Professor Catarina Reis for such achievement and for positioning in the spotlight with such prestigious mention.

https://lnkd.in/dArjC-R3

01/07/2022

On the next 6th of July, will take place at Faculdade de Farmácia of Universidade de Lisboa (FFUL) the Satelite Symposium of the 13th iMed ULisboa Meeting, “Advancing Drung Delivery”. This Satelite Symposio will have presentations of Professor Gordon L. Amidon and Professor Gregory Gregoriadis.

29/06/2022

On the next 7th of July, Universidade de Lisboa will held the Ceremony of Honorary Doctorate. The two awarded persons are Gordon Lewis Amidon and Gregory Gregoriadis, due to their notable work over the years.

No próximo dia 7 de julho, celebramos o percurso destes dois professores, na cerimónia de atribuição do Doutoramento Honoris Causa. Estás convidado a participar! 👉 https://bit.ly/3ndIJ7G

01/03/2022

This week, the members of iMed.ULisboa and , Maria Eugénia Meirinhos Cruz, Maria Luísa Corvo, Maria Bárbara Martins, Sandra Simões and Maria Manuela Gaspar have published the work "Liposomes as Tools to Improve Therapeutic Enzyme Performance", a review paper included in the Special Issue "A Commemorative Issue in Honor of Professor Gregory Gregoriadis: Liposomes for the Delivery of Drugs and Vaccines" from Pharmaceutics (https://doi.org/10.3390/pharmaceutics14030531).
Professor Gregory Gregoriadis is considered the pioneer of the use of liposomes as drug delivery systems. The authors would like to thank Gregory Gregoriadis for the consultancy and support to the research group in Lisbon, and the opportunity to participate in the fruitful meetings and courses in the liposomes field. Authors owe him his vision, inspiration and pioneering work that allowed the start of a new area of Pharmaceutical Technology and to provide weapons against many diseases.
Great work!

The drugs concept has changed during the last few decades, meaning the acceptance of not only low molecular weight entities but also macromolecules as bioagent constituents of pharmaceutics. This has opened a new era for a different class of molecules, namely proteins in general and enzymes in parti...

22/10/2021

The last sessions of our Symposium are live now! If you are registered tune in now via Zoom for Session 6, Session Gregory Gregoriadis and the Closing Cerimony of the 1st Symposium of Advanced Technologies for Drug Delivery

22/10/2021

Welcome to the second day of the 1st Symposium on Advanced Technologies for Drug Delivery! We are live again. If you are registered tune in now via Zoom for Session 4 & 5.

21/10/2021

Tune in now! If you are registered tune in now via Zoom for Session 3 & 4 of the 1st Symposium of Advanced Technologies for Drug Delivery

21/10/2021

Today! If you are registered, tune in now via Zoom for Session 1 & 2 of the 1st Symposium of Advanced Technologies for Drug Delivery

25/09/2021

The Advanced Technologies for Drug Delivery (ATDD) research group is pleased to announce the PhD Thesis defense of Jacinta Pinho, who got the PhD with distinction cm laude. Jacinta’s PhD Thesis defense entitled “Cancer chemotherapeutic agents using a nanotechnological approach” took place online on 16th September 2021 and was held by an honorable jury panel composed by: Professor Gert Storm (Faculty of Sciences from Utrecht University), Professor João Nuno Moreira (Faculty of Pharmacy from the University of Coimbra) and Professors and Researchers from Faculty of Pharmacy from the University of Lisbon (FFUL) (Matilde Castro as President of the Jury Panel, António Almeida, Cecília Rodrigues, Ana Paula Francisco and Manuela Gaspar).
Congratulations to Jacinta Pinho and her supervisors, Manuela Gaspar and Graça Soveral from FFUL and Angela Casini from Technical University of Munich!
Congratulations to ATDD/iMed.ULisboa and to everyone who collaborated in this work, from both national and international institutions!
 

21/09/2021

Meet the speakers of the 1st Symposium on Advanced Technology for Drug Delivery, by iMed.ULisboa, to take place via Zoom on the 21st and 22nd of October.
Registration and Abstracts must be submitted until September 30th (https://www.ff.ulisboa.pt/eventos/1-o-symposium-on-advanced-technologies-for-drug-delivery/).
We hope to see you there.

27/08/2021

Mariana Amaral, a student from our group, was awarded 1st place in the AIMS Meeting 2021 Research Competition Plenary Session with the work entitled “How Can Biomolecules Improve Mucoadhesion of Oral Insulin? A Comprehensive Insight using Ex-Vivo, In Silico, and In Vivo Models.”. Congratulations Mariana and for this recognition of a great work!