10/14/2025
Meet Catly!👋
Catly is a CI student in the Glycosomal Targeting in 𝘛𝘳𝘺𝘱𝘢𝘯𝘰𝘴𝘰𝘮𝘢 𝘣𝘳𝘶𝘤𝘦𝘪 Project! 🔬🧡🦠👩🏻🔬
Hear from Catly about her impactful research experience:
“I’ve been involved in Dr. Morris’ lab and the EPIC (GEN 4910) program since my junior year. In the Morris Lab, my research focuses on identifying and localizing potential drug targets and understanding drug uptake in 𝘛𝘳𝘺𝘱𝘢𝘯𝘰𝘴𝘰𝘮𝘢 𝘣𝘳𝘶𝘤𝘦𝘪, a protozoan parasite that causes African sleeping sickness. What makes trypanosomes so complex are their cellular mechanisms, like glucose metabolism, that are not yet fully understood. Our goal here is to expand our understanding of their cellular biology so that we can exploit it for drug targets. This past summer, I specifically investigated how drugs and inhibitors are trafficked to glycosomes, which are specialized peroxisomes that house essential glycolytic enzymes. To do this, I worked on purifying PTS-tagged (peroxisomal targeting sequence) eYFP proteins, which helps us characterize how these proteins are delivered to the glycosomes and potentially co-delivered with drugs.”