06/23/2026
A team of scientists from the Barbara Ann Karmanos Cancer Institute, Wayne State University, and institutions across the U.S., have published a landmark paper on the role of TGFBR1*6A, a naturally occurring genetic mutation in the TGFBR1 gene found in approximately 14 percent of the general population.
The study, "TGFBR1*6A and risk for colorectal cancer," published online June 9, 2026 in Cancer Communications, a Science Partner Journal with an impact factor of 24.9, focuses on TGFBR1*6A and how it influences a person’s risk of developing colorectal cancer. Dr. Boris Pasche, president and CEO of the Karmanos Cancer Institute and chair of the Wayne State University Department of Oncology, was the first to discover TGFBR1*6A as a cancer risk allele. Learn more at
Scientists at Wayne State University and the Karmanos Cancer Institute have published a landmark paper on the role of a naturally occurring genetic mutation