06/23/2026
A blood sample may soon reveal how genes behave deep inside living tissues.
Rice University Bioengineering's Jerzy Szablowski and Sho Watanabe developed a new approach for accurately mapping transcription profiles in living brain tissue using only a blood sample.
Their work marks the first demonstration of measuring transcription for targeted genes nondestructively in living tissue—an advance that could open new avenues for studying brain function, monitoring disease and evaluating therapies without invasive procedures.
Technology Networks recently highlighted the research and its potential impact.
New research introduces INTACT, a tool that combines RNA sensing and blood-based reporters to track gene expression in real time. The system could eventually enable large-scale monitoring of genes across multiple tissues.