10/12/2026
Researchers from Texas Tech and Texas Tech University Health Sciences Center (TTUHSC) are expanding undergraduate research experiences in biomedical engineering while exploring ways to better understand how cancer spreads.
Wei Li, professor of chemical engineering in the Texas Tech University - Whitacre College of Engineering, and his co-investigators Qiugang (Jay) Lu, assistant professor of chemical engineering, and Robert Bright, professor of immunology in the Department of Immunology and Molecular Microbiology at TTUHSC, received a $607,488 grant from the National Institutes of Health (NIH) to study circulating tumor cell (CTC) subtypes.
The team will evaluate characteristics of epithelial-mesenchymal transition (EMT) in CTCs, which is believed to be closely related to how cancer spreads from one site to the whole body. The process, known as metastasis, cause the majority of cancer-related mortalities.
Through this project, the team will develop a specially designed microchip, which will isolate and profile the CTC subtype cells from blood samples. The CTCs will be microscopically photographed at different magnifications so that researchers can understand their features at both the micrometer and nanometer levels. Then the team will explore AI-based profiling platforms to evaluate the images, which is expected to achieve super-high accuracy for profiling CTC subtypes.
Texas Tech Chemical Engineering
Texas Tech University Health Sciences Center Research and Innovation