Dyhydromatics LLC

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United States
Maynard, MA
Dyhydromatics LLC

US-based OEM of advanced high-pressure homogenizers for biotech, pharma, personal care, food/beverage, and cannabis. Direct-to-engineer support.

Proprietary ShearJet® & Reaction Chamber® for nanoemulsions, cell disruption, and advanced formulations.

03/19/2026

At Dyhydromatics, we're driven by precision and dedication. That’s why we're so inspired by the work of Force Blue and are proud to announce our official support for their mission again in 2026.

Force Blue retrains elite military veterans, redeploying their incredible skills to tackle critical marine conservation challenges. It’s a brilliant fusion of two causes we care deeply about: supporting our nation’s heroes and protecting our planet.

To play our part, we’re donating a portion of our proceeds to help fund their missions. We’re excited to contribute to a program that restores lives and our oceans. 🤝

Learn more about their work at forceblueteam.org.

03/09/2026

Elevating Personal Care, One Nanoparticle at a Time

Smaller particles. Bigger impact.

In personal care, experience is everything, from how a product feels on the skin to how well it actually works. And more often than not, that magic happens at the nanoscale.

By nano-sizing active ingredients, formulators can dramatically improve absorption, texture, and stability, leading to creams that melt seamlessly into the skin, serums that pe*****te deeper, and sunscreens that go on clear instead of solid white.

At Dyhydromatics, we’re seeing the impact firsthand. Technologies like high-shear processing and precision particle sizing are helping brands create luxurious, high-performance products without compromising on safety or shelf life.

In a market where consumers expect more, nano-enabled formulations aren't just a trend, they're the future of personal care products.

Learn more on our website: https://dyhydromatics.com/industries-applications/personal-care/

02/18/2026

Our team was honored to be recognized as a sponsor at the 2nd MET-I-CON International Conference in Nashik, Maharashtra, India (January 9–10, 2026).

Presented by MET’s Institute of Pharmacy (Bhujbal Knowledge City), the conference focused on future trends in pharma and included topics such as nanotechnology in drug delivery and AI-driven pharmaceutical innovations.

📸 Below are a few photos from the event, including the sponsor recognition award, our booth setup, and members of the Dyhydromatics India team.

01/15/2026

Looking for a high-pressure homogenization partner — not just a machine?

Dyhydromatics supports teams from early formulation and R&D through scale-up and commercial production. In this short feature video, you’ll get an overview of our ShearJet® processors, key applications, core capabilities, and global support network.

Ready to get started? Let’s discuss your next project: https://dyhydromatics.com/contact-us/

01/05/2026

New white paper from Karlsruhe Institute of Technology (KIT): Using the ShearJet® HL60 V2 High-Pressure Homogenizer for the emulsification and dispersion of food matrices.

Inside, you’ll find application examples including:
• Aroma oil emulsions for beverage flavor systems
• High-viscosity emulsions (high oil content)
• Melt emulsification (dairy) at controlled temperatures
• Oat-based beverage processing for improved uniformity and stability
• Pectin microgel particle production for advanced stabilization

📄 Download the full white paper: https://dyhydromatics.com/white-paper-using-shearjet-hl60-v2-high-pressure-homogenizer-for-emulsification-and-dispersion-of-food-matrices/ -form-kit-white-paper

12/23/2025

Merry Christmas from all of us at Dyhydromatics.

Wishing you and your loved ones a joyful holiday season and a happy, healthy New Year.

Thank you for your trust in Dyhydromatics and for the opportunity to support your innovations.

Holiday Hours: Closed December 24 - Reopening January 5
Emergency Support: David Hunter · +1 978-793-9980

Warm wishes,
The Dyhydromatics Team
dyhydromatics.com

12/06/2025

Don't miss the upcoming live webinar hosted by Dyhydromatics: Drug Release Rate Characterization of Double Nanoemulsions (W1/O/W)

📅 Thursday, December 11, 2025 - 11:00 AM EST
➡️ REGISTER NOW: https://us06web.zoom.us/webinar/register/WN_XDLmB3rFRUqn_uLXmx0A8w

Water-in Oil-in Water emulsions (W1/O/W) can be used to deliver a combination of hydrophobic and hydrophilic drugs by employing semipermeable water compartments within oil particles. Encapsulation efficiency and release rates are important characteristics of the formulation for delivery, stability, stealthiness, and storage life.

Delphi Scientific has developed novel processes to produce double emulsions using novel technologies for Continuous Emulsification. Additionally, they developed a quick screening method that yields drug release profiles from double nanoemulsions and helps expedite the development process.

Join Dyhydromatics as they host a webinar by Thomai Panagiotou, Ph.D., the President and CEO, Delphi Scientific, LLC.

👉 Click Here to Register for the Webinar: https://us06web.zoom.us/webinar/register/WN_XDLmB3rFRUqn_uLXmx0A8w

10/28/2025

Dyhydromatics to Exhibit at AAPS PharmSci 360 with Ascendia Pharmaceutical Solutions

📅 November 9-12, 2025
📍 Henry B. González Convention Center | San Antonio, TX
🔹 Booth 3025

Dyhydromatics will be exhibiting at AAPS PharmSci 360 in collaboration with our partner and leading CDMO, Ascendia Pharmaceutical Solutions. Together, we’re showcasing how advanced high-pressure homogenization and formulation development expertise accelerate innovation from R&D to commercial scale.

At the event, we’ll feature the ShearJet® HL60 V2 processor, our compact R&D processor engineered for scalability, precision, and consistency. Designed for sample volumes from approximately 3 mL to 500 mL and pressures up to 30,000 psi, the ShearJet HL60 V2 processor delivers precise, repeatable homogenization across nanoemulsions, liposomes, suspensions, and complex formulations.

Stop by our booth to learn how Dyhydromatics equipment and expertise, combined with Ascendia’s formulation and CDMO capabilities, can help streamline your path from concept to clinic.

Let’s Connect at the Show.

Schedule a meeting with our team to discuss your application or formulation needs.

👉 Book a Meeting: https://dyhydromatics.com/contact-us/

👉 Learn More About the ShearJet HL60 V2 Processor: https://dyhydromatics.com/equipment/small-volume-shearjet-hl60-v2/

👉 Visit Our Website: https://dyhydromatics.com/

09/30/2025

Novel Curcumin Nanoparticles Show Promise for Treating Dry Eye Disease - Engineered with the ShearJet® HL60

Delivering curcumin effectively to the eye has long presented challenges. This white paper, published in the Journal of Drug Delivery Science and Technology, examines how high-shear processing with the ShearJet® HL60 processor can be used to create stable curcumin nanoparticles for ophthalmic use.

Inside this report:

- How nano-sized curcumin may improve drug delivery and bioavailability for dry eye disease

- The process and benefits of high-shear homogenization for ophthalmic nanoformulations

- Supporting data and observations from recent research

For those interested in the potential of nanoparticle-based eye therapies, this white paper provides practical insights and recent findings.

Visit our site to learn more and access the full white paper: https://dyhydromatics.com/novel-curcumin-nanoparticles-show-promise-for-treating-dry-eye-disease-engineered-with-the-shearjet-hl-60/

09/08/2025

Breaking boundaries in formulation support—Globally 🌍

At Dyhydromatics, our commitment to innovation doesn’t stop at engineering the industry’s most reliable high-pressure homogenizers. We’ve established a global network of formulation and process development centers, making it easier than ever for customers to optimize processes, validate new formulations, or troubleshoot complex challenges—wherever they are.

Our global footprint gives you access to:

✅ Application experts for tailored solutions

✅ Proof-of-concept testing resources

✅ Hands-on guidance, responsive support, and results-driven collaboration—no matter the location

Whether you’re scaling up a new drug delivery system or perfecting a nanoemulsion, you get the same Dyhydromatics experience—personal, expert, and always accessible.

Explore our global network and discover how easy it is to tap into real formulation know-how, anywhere in the world: https://dyhydromatics.com/resources/proof-of-concept-testing-and-formulation-development/

09/03/2025

Introducing the ShearJet® HP1200 V2 Pilot-Scale Homogenizer!

For R&D teams and process engineers ready to scale up, our HP1200 V2 sets a new benchmark for pilot-scale high-pressure homogenization. Built for demanding applications—nanoemulsions, liposomes, cell disruption, and more—the HP1200 V2 delivers ShearJet performance, proven reliability, and exceptional scalability.

Why choose Dyhydromatics?

🇺🇸 US-Based OEM: Work directly with the engineers who design, build, and support your equipment.

💎 Diamond Reaction Chamber®: Our proprietary technology maximizes performance and durability.

🧪 1,500+ Formulations Processed: Unmatched application expertise.

🧑‍🔬 Direct-to-Expert Support: Get answers from people who truly understand your process.

Whether you’re moving from lab-scale to pilot, or optimizing a new bioprocess, the HP1200 Series V2 is engineered to deliver.

👉 See the HP1200 V2 in detail: https://dyhydromatics.com/equipment/pilot-scale-hp1200-series-v2/

08/27/2025

Small batch. Big performance.

When every milliliter matters, you need reliable, repeatable, and controlled homogenization.

The ShearJet® HL60 V2 delivers precision small-volume processing (from 3mL to 500mL) with real-time process monitoring and control — all in a compact, quiet, and efficient design.

✅ Gentle, consistent homogenization for sensitive formulations
✅ Integrated HMI for real-time process monitoring and control
✅ Compact footprint designed for small batch & R&D scale-up
✅ Proprietary Reaction Chamber® ensures consistent shear conditions and repeatable performance

🔗 Learn more: https://dyhydromatics.com/equipment/small-volume-shearjet-hl60-v2/

Address

63 Great Road
Maynard, MA
01754

Telephone

+19784610200

Website

http://www.dyhydromatics.com/

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