Shepherd Lab

Shepherd Lab We are interested in elucidating the fundamental cellular and molecular processes that underlie memory formation and neurological diseases.

In particular we are interested in the elucidation of the protein machinery at the synapse that governs long-term storage of information, and how basic cell biological processes have been elaborated in neurons for the purpose of modulating synaptic transmission. In addition, we are interested in how these processes go awry in neurological diseases. The overall goal of our research program is to in

vestigate the role of activity-dependent processes, and the requisite gene programs, involved in synaptic plasticity and how these processes go awry in neurological disorders.

We've been a little slack in updating you with news, but here's a talk I gave TEDMED that summarizes our recent work in ...
08/08/2019

We've been a little slack in updating you with news, but here's a talk I gave TEDMED that summarizes our recent work in a general audience format.

Do you remember your oldest memory? Jason Shepherd clearly recalls a childhood filled with questioning the world around him, which naturally lead to a life of scientific discovery. As a Neurobiologist, Jason's curiosity spurred an unexpected finding as he studied the biology behind memory s...

The Shepherd lab is excited to be receiving funding from the Alzheimer's Association!
11/01/2018

The Shepherd lab is excited to be receiving funding from the Alzheimer's Association!

Get information and resources for Alzheimer's and other dementias from the Alzheimer's Association.

01/16/2018

, a master regulator of , contains sequence elements related to Gag genes. Here, 2 studies show that Arc retains retroviral-like capsid-forming ability and can transmit mRNA between cells. http://bit.ly/2CVPe60 , http://bit.ly/2Fv8PvR

We are very excited to share our latest paper, published in Cell!
01/11/2018

We are very excited to share our latest paper, published in Cell!

The neuronal protein Arc is evolutionarily related to retrotransposon Gag proteins and forms virus-like capsid structures that can transfer mRNA between cells in the nervous system.

The lab made the University home page!
08/10/2017

The lab made the University home page!

Like the rest of the body, the brain loses flexibility with age, impacting the ability to learn, remember, and adapt. Now, scientists at University of Utah Health report they can rejuvenate the plasticity of the mouse brain, specifically in the visual cortex. Published today in PNAS, the study shows...

08/08/2017

Second paper, with authors - Kyle Jenks, Elissa Pastuzyn and Andrew Taibi from the lab.

National Academy of Sciences

It's been a great summer for the lab, with two papers published! Here's the first: lead (and sole!) author - Elissa Past...
08/08/2017

It's been a great summer for the lab, with two papers published! Here's the first: lead (and sole!) author - Elissa Pastuzyn

Angelman syndrome (AS) is a neurodevelopmental disorder that results from deletions or mutations in chromosome 15, which usually includes the UBE3A gene. Ube3A protein is an E3 ubiquitin ligase that ubiquitinates proteins and targets them for degradation. The immediate-early gene Arc, a master regul...

02/13/2017

The Shepherd Lab received an amazing score on a recent NIH R01 grant submission that ensures funding for the next 5 years! This all due to the hard work of the lab and is much deserved.

12/05/2016

Honored to be one of the 2016 Matilda Ziegler Foundation grant awardees for our work investigating the molecular mechanisms of critical period plasticity in visual cortex!

The E. Matilda Ziegler Foundation for the Blind, Inc. (EMZ Foundation) was founded in New York City in 1907 by Electa Matilda Ziegler (1841-1932), the mother of a blind son. The EMZ Foundation announces the availability of funds to support promising young investigators performing innovative vision r...

10/12/2016

Congrats to Andrew Taibi for passing his thesis proposal defense and becoming the second Shepherd Lab graduate student to qualify to Ph.D. candidacy!

Address

36S Wasatch Drive, 4340 Sorenson Molecular Biotechnology Building
Salt Lake City, UT
84132

Alerts

Be the first to know and let us send you an email when Shepherd Lab posts news and promotions. Your email address will not be used for any other purpose, and you can unsubscribe at any time.

Share