BiotechIllinois

BiotechIllinois The Roy J.Carver Biotechnology Center provides state-of-the-art research infrastructure to investigators.

Our portfolio includes core research facilities supporting genomics,proteomics,metabolomics, bioinformatics,flow cytometry and translational medical

The Biotechnology Center, Flow Cytometry has a new name: Cytometry & Microscopy to Omics (CMtO). While maintaining our l...
11/16/2021

The Biotechnology Center, Flow Cytometry has a new name: Cytometry & Microscopy to Omics (CMtO).

While maintaining our long-term core services in cytometry, the CMtO core will also utilize advanced microscopy techniques to gain a deeper understanding of cell sorting and analysis, while also enabling cutting-edge spatial and single cell omics. The facility is therefore being instrumented to integrate cytometry and microscopy with omics to offer 10x Genomics Spatial Gene Expression and 10X Chromium Single Cell Gene Expression, as well as Proteomics on the same tissue sections and single cells. As one of the instruments required to accomplish these goals, the CMtO facility has recently purchased a Thermo Fisher Bigfoot Spectral Cell Sorter and is evaluating investments in next generation cytometry as a means to update and enhance its current analyzers across the campus. To facilitate this transition, the CMtO facility is also acquiring a group of support instruments, which include a BSL2 capable Cryostat, Microtome, Thermal Cyclers, and Cell Counters. In addition, the Zeiss LSM 980 with Airyscan 2 is being constructed as an integrated confocal and widefield microscope that will include Spectral-GaAsP, dedicated NIR Lasers and detectors, 2-photon capabilities, and custom configured color and black and white cameras. This robust state-of-the art fundamental instrumentation platform will fully support current and future Visium Transcriptomics and Proteomics projects. Please contact Dr. Sivaguru, Director of CMtO ([email protected]) for further information about these exciting and game changing developments for the services offered.
CMtO Webpage: https://biotech.illinois.edu/cmto
New Email for Appointments, Training and Project Consultation: [email protected]

Whereas most genomics research is based on getting information from DNA, a team of UIUC and University of Texas research...
05/19/2020

Whereas most genomics research is based on getting information from DNA, a team of UIUC and University of Texas researchers is using DNA nicking and sequencing to also store data. By introducing nicks in native E.coli DNA, the Lincoln's Gettysburg Address and a 14 kb image of the Lincoln Memorial were encoded in DNA fragments. The nicked fragments were converted into a library, sequenced on an Illumina MiSeq and the data was decoded with specialized algorithms. This method is able to encode data in native DNA with a cost that is orders of magnitude lower than previous approaches that used synthetic DNA. Dr. Olgica Milenkovic, Professor in Electrical and Computing Engineering, and Dr. Huimin Zhao, Professor at the Carl R. Woese Institute for Genome Biology, were the lead authors in the paper.

Here is a link to the paper:
https://www.nature.com/articles/s41467-020-15588-z

The Metabolomics Lab at University of Illinois has a suite of instruments (GC/MS and LC/MS) and related software package...
03/05/2020

The Metabolomics Lab at University of Illinois has a suite of instruments (GC/MS and LC/MS) and related software package for metabolite analysis. These mass spectrometry-based setups can achieve highly sensitive quantitative analysis, very accurate metabolite identification, and much more. The instrument platform is well suited to perform targeted metabolite analysis (quantitatively and qualitatively) and untargeted metabolite profiling for samples up to BSL-2.

The Protein Sciences Facility is staffed by Ph.D. scientists who collectively have several decades of experience working...
02/11/2020

The Protein Sciences Facility is staffed by Ph.D. scientists who collectively have several decades of experience working with and characterizing proteins from diverse systems. We provide a variety of proteomics services, including protein identification, detection of PTMs, isotopic label based and label-free quantitation, and native protein characterization. We have nano-flow LC systems and three Orbitrap mass spectrometers: an Orbitrap Fusion, a Q Exactive HF-X, and a Q Exactive UHMR (Ultra High Mass Range). For direct infusion, we also have two Advion TriVersa NanoMate chip-based robots. Data analysis is done with Mascot, Proteome Discoverer, and MaxQuant. We are available for consultations about sample preparation, data interpretation, and bioinformatics analysis. https://biotech.illinois.edu/proteinsciences

The Functional Genomics Lab provides services using high throughput platforms  for gene expression, genotyping, methylat...
02/05/2020

The Functional Genomics Lab provides services using high throughput platforms for gene expression, genotyping, methylation assays and microbial amplicon sequencing. Technologies available include Fluidigm Microfluidics, Illumina Bead Arrays, Quantitative PCR, as well as DNA, RNA quantitation and quality assessment. Amplicon libraries can be sequenced on either Illumina MiSeq or NovaSeq platforms as well as PacBio Sequel II for long reads.

Dr. Alvaro Hernandez, Director of DNA Services and  Dr. Mark Band, Director of Functional Genomics along with Chris Wrig...
01/13/2020

Dr. Alvaro Hernandez, Director of DNA Services and Dr. Mark Band, Director of Functional Genomics along with Chris Wright, Assistant Director, DNA services are at PAG XXVIII Conference, booth 205!

11/13/2019

The Carver Biotechnology Center’s High Performance Computational Biology (HPCBio) https://hpcbio.illinois.edu/ bioinformatics group is planning multiple workshops for the upcoming winter/spring. These training opportunities include in-depth and hands-on workshops covering an array of topically relevant and up-to-date topics, including Linux/bash, R, traditional RNA-Seq Analysis,10X Single Cell RNA-Seq Analysis, and Microbial Profiling Analysis. Workshops are offered year-round, with materials and lectures posted online https://hpcbio.illinois.edu/hpcbio-workshops. The HPCBio team also offers custom data analysis services for a broad range of applications.

Address

1206 W Gregory
Urbana, IL
61801

Opening Hours

Monday 8:30am - 5pm
Tuesday 8:30am - 5pm
Wednesday 8:30am - 5pm
Thursday 8:30am - 5pm
Friday 8:30am - 5pm

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